Background: Translational research is an evolving discipline that is intended to bridge the gaps between basic science\nresearch, clinical research, and implementation in clinical practice. It is a fluid, multidirectional process that requires strong\ninterdisciplinary collaboration to produce research that is relevant to end-users.\nPurpose of this review: This review summarizes current perspectives on translational research and outlines its relevance\nand importance to kidney transplantation research.\nSources of information: Sources of information used for this review include published reports, articles, and research\nfunding websites.\nFindings: Tissue typing is used as an in-depth example of how translational research has been applied in the\nfield of kidney transplant medicine, and how it has resulted in successful implementation of diagnostic and\nmanagement options for sensitized individuals undergoing kidney transplantation. The value of actively involving\nkidney transplant stakeholders (patients, caregivers, and clinicians) in setting research priorities and determining relevant\noutcomes for future investigation is also discussed.\nLimitations: This is a narrative review of the literature which has been partly influenced by the perspectives\nand experiences of its authors.\nImplications: Translational and patient-oriented research practices should be incorporated into future research\nendeavours in the field of kidney transplantation in order to create beneficial change in clinical practice and\nimprove patient outcomes.\nWhat was known before: Translational research which engages patients in the investigative process can enhance\nthe likelihood that medical discoveries will have a meaningful impact at the bedside.\nWhat this adds: This article applies current perspectives on translational research and patient engagement to the field\nof kidney transplantation, illustrating how these approaches have led to significant advancements in the field. It provides\nfurther justification for deliberate, targeted efforts to cross-collaborate and incorporate the patient voice into kidney\ntransplant research.
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